THE CLINICAL TRIAL

True Collagen

Our groundbreaking Clinical Trial is a major step forward in collagen research - an independently run Brave Standard Clinical Trial that confirms the whole-body benefits of True Collagen.

Led by Dr. Jenna Macciochi, Director of Science and Innovation at Ancient + Brave, the study explored the efficacy of daily bovine collagen supplementation in healthy women aged 35–55.

Whole body

health

Improvement

80

Felt more energised throughout the day

90

Found they recovered faster from exercise

70

Noticed an improvement in sleep quality

Reduction

73

Found that they experienced less pain or stiffness and greater ease of movement

Improvement

76

Increase in skin hydration

100

Saw an improvement in skin elasticity

36

Increase in skin radiance

Reduction

100

Saw a reduction in fine lines & wrinkles

43

Reduction in redness & inflammation

31

Reduction in collagen breakdown for firmer skin

Skin

Hair & nails

Improvement

63

Saw an increase in nail growth and strength

Reduction

77

Noticed less hair breakage

By investing in our rigorous, independent clinical trial, we’ve provided assurance that True Collagen peptides are clinically effective and backed by science.

Dr Jenna Macciochi
Director of Science & Innovation

I’m obsessed with True Collagen.
When I take it I feel the difference

Davina McCall
Television presenter
    True Collagen
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    Key study results

    Skin Hydration

    76% of participants saw an improvement

    True Collagen is clinically proven to improve skin hydration: The Corneometer - a gold-standard device for measuring skin hydration - found that 100% of participants taking True Collagen experienced an improvement in skin hydration compared to placebo. After 6 weeks, skin hydration increased by 63%. After 12 weeks, hydration levels further improved to 76%. These results confirm that True Collagen deeply nourishes the skin from within, delivering long-lasting hydration for a visibly healthier, more radiant complexion.

    True Collagen
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    Key study results

    Skin barrier function

    100% of participants saw an improvement

    True Collagen is clinically proven to reduce Transepidermal Water Loss (TEWL): TEWL measures how much moisture escapes from the skin—a key indicator of skin barrier strength and hydration retention. Clinical testing showed that 100% of participants experienced an improvement. After 6 weeks, TEWL decreased by 17%, meaning their skin retained more moisture. By 12 weeks, this improvement increased to 27%, confirming that True Collagen helps strengthen the skin barrier, locking in hydration for a smoother, healthier, and more resilient complexion.

    True Collagen
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    Key study results

    Collagen Breakdown

    100% of participants saw a reduction

    True Collagen is clinically proven to reduce collagen breakdown: The Vivascope—a trusted tool for assessing skin structure, including the epidermis and dermis—found that True Collagen helps preserve skin integrity by minimising collagen fragmentation (i.e. breakdown). After 6 weeks, collagen breakdown decreased by 18%, with 66% of participants experiencing improvement. After 12 weeks, these benefits increased to a 31% reduction, with 87% of participants showing positive changes.

    True Collagen
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    Key study results

    Fine lines / wrinkles

    100% of participants saw an improvement

    True Collagen is clinically proven to reduce the appearance of fine lines: The Profilometry—a precise tool for measuring skin texture and wrinkle depth—found that True Collagen visibly smoothes the skin. After 6 weeks, 100% of participants experienced an 8% improvement in fine lines. By 12 weeks, this improvement increased to an 18% reduction in fine lines. These results confirm that True Collagen helps to refine skin texture, promoting a smoother, more youthful-looking complexion.

    Looking for a deeper dive?

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    Trial results

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