THE CLINICAL TRIAL

True Collagen

Our groundbreaking Clinical Trial is a major step forward in collagen research - an independently run Brave Standard Clinical Trial that confirms the whole-body benefits of True Collagen.

Led by Dr. Jenna Macciochi, Director of Science and Innovation at Ancient + Brave, the study explored the efficacy of daily bovine collagen supplementation in healthy women aged 35–55.

Whole body

health

A woman with long red hair, wearing a brown sweater, stands against a backdrop of dark leafy vines with her eyes closed, enjoying the sunlight on her face.
Improvement

80

Felt more energised throughout the day

90

Found they recovered faster from exercise

70

Noticed an improvement in sleep quality

Reduction

73

Found that they experienced less pain or stiffness and greater ease of movement

*Based on participant-reported responses at week 12 in the True Collagen group (n=30) of a 12-week, independent, double-blind, randomised, placebo-controlled trial in 60 healthy women aged 35–55. Percentages show participants giving the most positive response; results shown were significantly higher than placebo.

Improvement

76

Increase in skin hydration

100

Saw an improvement in skin elasticity

36

Increase in skin radiance

Reduction

100

Saw a reduction in fine lines & wrinkles

43

Reduction in redness & inflammation

31

Reduction in collagen breakdown for firmer skin

Skin

Close-up of a persons right eye with brown iris, surrounded by curly reddish-brown hair and smooth, sunlit skin. Eyebrow is visible, and there is a soft shadow on the cheek.

*Independent, double-blind, randomised, and placebo-controlled 12-week clinical trial in 60 healthy UK females aged 35-55. Average change from baseline in the True Collagen group (n=30), measured using skin assessment instruments. All changes shown were statistically significant from baseline and compared with placebo.

Hair & nails

A woman with long, curly dark hair stands outdoors, turned away and looking to the right. She is wearing a sleeveless top, and lush green foliage surrounds her in the background.
Improvement

63

Saw an increase in nail growth and strength

Reduction

77

Noticed less hair breakage

“

By investing in our rigorous, independent clinical trial, we’ve provided assurance that True Collagen peptides are clinically effective and backed by science.

Dr Jenna Macciochi
Director of Science & Innovation

*Based on participant-reported responses at week 12 in the True Collagen group (n=30) of a 12-week, independent, double-blind, randomised, placebo-controlled trial in 60 healthy women aged 35–55. Percentages show participants giving the most positive response; results shown were significantly higher than placebo.

“

I’m obsessed with True Collagen.
When I take it I feel the difference

Davina McCall
Television presenter
A woman with long brown hair and a white blouse sits on an outdoor couch, smiling and holding a bottled drink. There are green plants and white flowers in the background.
    True Collagen
    Placebo

    Key study results

    Skin Hydration

    76% average increase in skin hydration

    Hydration was measured on the cheek with a Corneometer®, which reads the water content of the skin’s outer layers. In the True Collagen group, average hydration rose by 63% at week 6 and 76% at week 12. The placebo group changed by 2% over the same period.

    True Collagen
    Placebo

    Key study results

    Skin barrier function

    27% average improvement in skin barrier function

    Transepidermal Water Loss (TEWL) measures how much moisture escapes from the skin - a key indictor of skin barrier strength and hydration retention. In the True Collagen group, average TEWL decreased by 17% at week 6 and 27% at week 12. This improvement was statistically significant compared to the placebo group.

    True Collagen
    Placebo

    Key study results

    Collagen Structure

    31% average reduction in collagen fragmentation

    The skin’s collagen network was imaged beneath the surface using confocal microscopy (VivaScope®). Expert graders scored how fragmented the collagen fibres appeared, where a lower score means a more intact network. In the True Collagen group, fragmentation scores fell by 18% at week 6 and 31% at week 12. The placebo group fell by 7%.

    True Collagen
    Placebo

    Key study results

    Wrinkle Depth

    18% average reduction in wrinkle depth around the eyes

    Fine lines were measured using profilometry. A silicone replica of the crow’s-feet area is taken and scanned to quantify the depth of lines. In the True Collagen group, average wrinkle depth fell by 8% at week 6 and 18% at week 12. The placebo group changed by 1%.

    *Double-blind, randomised, and placebo-controlled clinical trial in 60 healthy UK females aged 35-55 to evaluate the efficacy of True Collagen over 12 weeks. Results independently measured using skin assessment instruments. 

    Looking for a deeper dive?

    Download now

    A black and gold pouch labeled Ancient Brine is pouring a white powder into a tall, black container against a neutral background.

    Trial results

    Three brown glass jars with black lids, each labeled differently: True Creative (green), True Nurture (red), and True Integration (blue), set against a beige background.

    Build your ritual

    Take our nutritionist-designed quiz and receive recommendations personalised to your unique needs.

    Take our quiz

    Further Studies

      A hand pours powder from a blue packet into a textured ceramic mug against a light pink background.
      Clinical results

      Wild Collagen

      Significantly improved multiple markers of skin and whole-body health, delivering visible and measurable benefits in beauty, digestion, sleep, and recovery.

      Improvement

      137

      Increase in skin hydration

      Reduction

      100

      Saw a reduction in fine lines and wrinkles

      74

      Noticed less joint stiffness & discomfort

      A jar labeled Ancient + Brave True Omegas+ sits on a dark tray next to several yellow omega oil capsules, all lit by warm sunlight.
      Citizen Scientist Feedback

      True Omegas+

      Significantly improved multiple markers of skin and whole-body health, delivering visible and measurable benefits in beauty, digestion, sleep, and recovery.

      100

      Reported feeling better overall

      100

      Said they would recommend to a friend

      100

      Thought it very effective in supporting their wellbeing