THE CLINICAL TRIAL

True Collagen

Our groundbreaking Clinical Trial is a major step forward in collagen research - an independently run Brave Standard Clinical Trial that confirms the whole-body benefits of True Collagen.

Led by Dr. Jenna Macciochi, Director of Science and Innovation at Ancient + Brave, the study explored the efficacy of daily bovine collagen supplementation in healthy women aged 35–55.

    True Collagen
    Placebo

    Key study results

    Skin Hydration

    76% average increase in skin hydration

    Hydration was measured on the cheek with a Corneometer®, which reads the water content of the skin’s outer layers. In the True Collagen group, average hydration rose by 63% at week 6 and 76% at week 12. The placebo group changed by 2% over the same period.

    True Collagen
    Placebo

    Key study results

    Skin Barrier Function

    27% average improvement in skin barrier function

    Transepidermal Water Loss (TEWL) measures how much moisture escapes from the skin - a key indictor of skin barrier strength and hydration retention. In the True Collagen group, average TEWL decreased by 17% at week 6 and 27% at week 12. This improvement was statistically significant compared to the placebo group.

    True Collagen
    Placebo

    Key study results

    Collagen Structure

    31% average reduction in collagen fragmentation

    The skin’s collagen network was imaged beneath the surface using confocal microscopy (VivaScope®). Expert graders scored how fragmented the collagen fibres appeared, where a lower score means a more intact network. In the True Collagen group, fragmentation scores fell by an average of 18% at week 6 and an average of 31% at week 12. The placebo group fell by 7%.

    True Collagen
    Placebo

    Key study results

    Wrinkle Depth

    18% average reduction in wrinkle depth around the eyes

    Fine lines were measured using profilometry. A silicone replica of the crow’s-feet area is taken and scanned to quantify the depth of lines. In the True Collagen group, average wrinkle depth fell by 8% at week 6 and 18% at week 12. The placebo group changed by 1%.

    *Double-blind, randomised, and placebo-controlled clinical trial in 60 healthy UK females aged 35-55 to evaluate the efficacy of True Collagen over 12 weeks. Results independently measured using skin assessment instruments. 

    Whole Body

    Health

    A woman with long red hair, wearing a brown sweater, stands against a backdrop of dark leafy vines with her eyes closed, enjoying the sunlight on her face.
    Improvement

    80

    Felt more energised throughout the day

    90

    Found they recovered faster from exercise

    70

    Noticed an improvement in sleep quality

    Reduction

    73

    Found that they experienced less pain or stiffness and greater ease of movement

    *Based on participant-reported responses at week 12 in the True Collagen group (n=30) of a 12-week, independent, double-blind, randomised, placebo-controlled trial in 60 healthy women aged 35–55. Percentages show participants giving the most positive response; results shown were significantly higher than placebo.

    Improvement

    76

    Average increase in skin hydration

    100

    Saw an improvement in skin elasticity

    27

    Average improvement in skin barrier function

    Reduction

    100

    Saw a reduction in wrinkle depth

    43

    Average reduction in skin redness

    31

    Average reduction in collagen fragmentation

    Skin

    Close-up of a persons right eye with brown iris, surrounded by curly reddish-brown hair and smooth, sunlit skin. Eyebrow is visible, and there is a soft shadow on the cheek.

    *Independent, double-blind, randomised, and placebo-controlled 12-week clinical trial in 60 healthy UK females aged 35-55. Average change from baseline in the True Collagen group (n=30), measured using skin assessment instruments. All changes shown were statistically significant from baseline and compared with placebo.

    Hair & Nails

    A woman with long, curly dark hair stands outdoors, turned away and looking to the right. She is wearing a sleeveless top, and lush green foliage surrounds her in the background.
    Improvement

    63

    Saw an increase in nail growth and strength

    Reduction

    77

    Noticed less hair breakage

    “

    By investing in our rigorous, independent clinical trial, we’ve provided assurance that True Collagen peptides are clinically effective and backed by science.

    Dr Jenna Macciochi
    Director of Science & Innovation

    *Based on participant-reported responses at week 12 in the True Collagen group (n=30) of a 12-week, independent, double-blind, randomised, placebo-controlled trial in 60 healthy women aged 35–55. Percentages show participants giving the most positive response; results shown were significantly higher than placebo.

    “

    I’m obsessed with True Collagen.
    When I take it I feel the difference

    Davina McCall
    Television presenter
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    Trial results

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    Further Studies

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      Clinical results

      Wild Collagen

      Significantly improved multiple markers of skin and whole-body health, delivering visible and measurable benefits in beauty, digestion, sleep, and recovery.

      Improvement

      137

      Increase in skin hydration

      Reduction

      100

      Saw a reduction in fine lines and wrinkles

      74

      Noticed less joint stiffness & discomfort

      A jar labeled Ancient + Brave True Omegas+ sits on a dark tray next to several yellow omega oil capsules, all lit by warm sunlight.
      Citizen Scientist Feedback

      True Omegas+

      Significantly improved multiple markers of skin and whole-body health, delivering visible and measurable benefits in beauty, digestion, sleep, and recovery.

      100

      Reported feeling better overall

      100

      Said they would recommend to a friend

      100

      Thought it very effective in supporting their wellbeing

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